Isolation of secondary metabolites from an Arctic bacterium, Pseudomonas aeruginosa and their antimicrobial activities
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- Isolation of secondary metabolites from an Arctic bacterium, Pseudomonas aeruginosa and their antimicrobial activities
- Youn, Ui Joung
Kim, Min Ju
Han, Se Jong
Jung, Han Yim
- Life Sciences & Biomedicine - Other Topics
- Pseudomonas aeruginosa; Antimicrobial activity; Diketopiperazine; Phenazine; Pseudomonadaceae
- Issue Date
- Youn, Ui Joung., et al. 2016. Isolation of secondary metabolites from an Arctic bacterium, Pseudomonas aeruginosa and their antimicrobial activities. Korean Journal of Microbiology, 52(4): 415-420.
- Chemical study of an Arctic bacterium, Pseudomonas aeruginosa (Pseudomonadaceae) led to the isolation of two
diketopiperazines 1 and 2, two phenazine alkaloids 3 and 4, and an indole carbaldehyde 5, along with a benzoic acid derivative 6. The
structures of the compounds were confirmed by 1D and 2D NMR, and MS experiments, as well as by comparison of their data with
published values. Among the isolates, compounds 5 and 6 were isolated for the first time from P. aeruginosa of the seawater of Arctic
Chuckchi Sea. Antimicrobial activities of compounds 1？6 against a Staphylococcus aureus and Candida albicans were evaluated.
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