KOPRI Repository

Chemical Constituents from the Apical Bud of Gardenia sootepensis and Their Bioactivity

Cited 0 time in scopus
Metadata Downloads
Title
Chemical Constituents from the Apical Bud of Gardenia sootepensis and Their Bioactivity
Other Titles
Gardenia sootepensis의 끝눈으로부터 생리활성 성분
Authors
Youn, Ui Joung
Chang, Leng Chee
Subject
Pharmacology & Pharmacy
Keywords
Flavonoid; Gardenia sootepensis; Nitric oxide; Rubiaceae
Issue Date
2017
Citation
Youn, Ui Joung, Chang, Leng Chee. 2017. "Chemical Constituents from the Apical Bud of Gardenia sootepensis and Their Bioactivity". Korean Journal of Pharmacognosy, 48: 113-118.
Abstract
Bioassay guided fractionation and isolation of the CH2Cl2 extract from the apical bud of Gardenia sootepensis (Rubiaceae) led to the isolation of five known flavonoids (1-5). The structures of the compounds were determined by 1D and 2D NMR, and MS experiments, as well as by comparison of their data with published values. Compounds 1-5 were isolated for the first time from this plant source. The isolated compounds were evaluated for their cancer chemopreventive potential based on their ability to inhibit nitric oxide (NO) production. Among the isolates, compound 4 exhibited considerable NO inhibitory activity with an IC50 value of 13.8 ?M.
URI
http://repository.kopri.re.kr/handle/201206/6092
Files in This Item
General Conditions
      ROMEO Green
    Can archive pre-print and post-print or publisher's version/PDF
      ROMEO Blue
    Can archive post-print (ie final draft post-refereeing) or publisher's version/PDF
      ROMEO Yellow
    Can archive pre-print (ie pre-refereeing)
      ROMEO White
    Archiving not formally supported

    qrcode

    Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

    Browse