Antibacterial potential of Antarctic Lichens against Human Pathogenic Gram Positive Bacteria
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- Antibacterial potential of Antarctic Lichens against Human Pathogenic Gram Positive Bacteria
- Other Titles
- 인감감염 그람양성미생물에 대한 남극지의류의 항미생물 활성
- Paudel, Babita
Hong, Soon Gyu
Yim, Joung Han
Shin, Hyun Woung
Lee, Jin Sung
Bhattarai, Hari Datta
- Pharmacology & Pharmacy
- Antarctic lichens; Antibacterial activity; Gram(+) bacteria; Minimum inhibitory concentrati
- Issue Date
- Wiley Interscience
- Paudel, Babita, et al. 2008. "Antibacterial potential of Antarctic Lichens against Human Pathogenic Gram Positive Bacteria". PHYTOTHERAPY RESEARCH, 22(9): 1269-1271.
- Extracts from five Antarctic lichens (L3, Stereocaulon alpinum;L5, Ramalina terebrata;L6, Caloplaca sp.;L8, Lecanora sp.;and L17, Caloplaca regalis) were tested for antimicrobial activities against several clinically important microbes by disk diffusion. The minimum inhibitory concentration (MIC) of each extract was determined by broth dilution method. Extracts from L3, L5, L6 and L8 were active against two Gram(+) strains. B. subtilis was more sensitive to lichen extracts (except L5) than S. aureus. The MIC of lichen extracts against B. subtilis and S. aureus was observed from 36.7 ？0.3 to 953.8？85.8 ？g ml-1 and 68.5？0.6 to >1000 ？g ml-1, respectively. Comparisons of MIC values of Antarctic lichen crude extracts to previously published MIC values of some reported lichen metabolites against Gram(+) bacteria indicated that Antarctic lichens might be an enriched source of effective antibacterial agents against clinically relevant Gram(+) species.
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