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Usimines A-C, Bioactive Usnic Acid Derivatives from the Antarctic Lichen Stereocaulon alpinum

Cited 27 time in wos
Cited 28 time in scopus
Title
Usimines A-C, Bioactive Usnic Acid Derivatives from the Antarctic Lichen Stereocaulon alpinum
Other Titles
남극 지의류 Stereocaulon alpinum으로부터 생물활성을 가지는 Usnic Acid 유도체
Authors
Lee, Hong Kum
Oh, Hyuncheol
Yim, Joung Han
Seo, Changon
Sohn, Jae Hak
Subject
Plant SciencesPharmacology & Pharmacy
Keywords
Antarctic LichenStereocaulon alpinumUsnic Acid Derivatives
Issue Date
2008
Publisher
American Chemical Society and American Society of Pharmacognosy
Citation
Lee, Hong Kum, et al. 2008. "Usimines A-C, Bioactive Usnic Acid Derivatives from the Antarctic Lichen Stereocaulon alpinum". JOURNAL OF NATURAL PRODUCTS, 71(1): 710-712.
Abstract
Usimines A-C (1?3), three new usnic acid derivatives, have been isolated from a MeOH extract of the Antarctic lichen Stereocaulon alpinum by various chromatographic methods. The structures of 1?3 were determined by analysis of their spectroscopic data (NMR, UV, MS) and by chemical methods. The known compound usnic acid (4) was also obtained. Compounds 1?4 showed moderate inhibitory activity against therapeutically targeted protein tyrosine phosphatase 1B (PTP1B).
URI
https://repository.kopri.re.kr/handle/201206/6335
DOI
http://dx.doi.org/10.1021/np070464b
Type
Article
Indexed
SCI
Appears in Collections  
2006-2010, Procurement and utilization of polar genetic resources (06-10) / Lee, Hong Kum; Yim, Joung Han (PE06050, PE07050, PE08050, PE09050, PE10050)
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