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Chemical Constituents of Fermented Noni (Morinda citrifolia) Juice Exudates and Their Biological Activity

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Title
Chemical Constituents of Fermented Noni (Morinda citrifolia) Juice Exudates and Their Biological Activity
Other Titles
발효된 노니주스로부터 화학성분 및 생리활성
Authors
Youn, Ui Joung
leng chee chang
Subject
Pharmacology & Pharmacy
Keywords
Morinda citrifolia; alkyl disaccharide; anti-inflammatory activity
Issue Date
2017
Citation
Youn, Ui Joung, leng chee chang. 2017. "Chemical Constituents of Fermented Noni (Morinda citrifolia) Juice Exudates and Their Biological Activity". Natural Product Sciences, 23(1): 16-20.
Abstract
In a continuing study of the fermented noni (Morinda citrifolia) juice exudates, five compounds, heptanyl 2-O-β-D-xylofuranosyl-(1→6)-β-D-glucopyranoside (1), n-butyl β-D-glucopyranoside (2), (1S)-(3-ethenyl-phenyl)-1,2-ethanediol (3), (2S)-2-hydroxybutanedioic acid (4), and daucosterol (5) were isolated from the buthanol partition of the extract. The structures of the isolates were identified by 1D and 2D NMR, and MS experiments, as well as by comparison of their data with the published values. Among the isolates, compounds 1 - 3 were isolated for the first time from the plant species. The isolated compounds were evaluated for their cancer chemopreventive potential based on their ability to inhibit nitric oxide (NO) production and tumor necrosis factor alpha (TNF-α)-induced NF-κB activity, and quinonone reductase-1 (QR1)-inducing effect.
URI
http://repository.kopri.re.kr/handle/201206/6492
DOI
http://dx.doi.org/10.20307/nps.2017.23.1.16
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