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Enhancement of the Stability and Solubility of Prodigiosin Using β-Cyclodextrin in Seawater

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Title
Enhancement of the Stability and Solubility of Prodigiosin Using β-Cyclodextrin in Seawater
Other Titles
β-Cyclodextrin을 이용한 해수에서의 Prodigiosin의 안정성과 용해도 향상
Authors
Kim, Tai Kyoung
Park, Heeyong
Yim, Joung Han
Han, Se Jong
Subject
Engineering
Keywords
Algicidal activity; Chattonella antiqua; Cyclodextrin; Inclusion complex; Prodigiosin
Issue Date
2012
Citation
Kim, Tai Kyoung, et al. 2012. "Enhancement of the Stability and Solubility of Prodigiosin Using β-Cyclodextrin in Seawater". Biotechnology and Bioprocess Engineering, 27: 109-113.
Abstract
This research was to examine the effects of various cyclodextrins on the solubility and stability of prodigiosin in seawater. Among them, β-cyclodextrin was found to have the best efficiency and formation of the inclusion complex was saturated when prodigiosin and β-cyclodextrin were mixed in a ratio of 1:8 and shaken at 25℃ and pH 8.0 for 6 h. The maximum algicidal activity against Chattonella antiqua using the inclusion complex stored at 4℃ for 5 weeks of culture was obtained, 52.28 ± 3.41%,which was about 5.0 fold higher than that of control. Our results suggest that inclusion complexes of prodigiosin and β-cyclodextrin could serve as effective algicidal agents.
URI
http://repository.kopri.re.kr/handle/201206/6611
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