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Optimization of medium for carotenoids production by Arthrobacter sp. PAMC 25486 using response surface methodology

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Title
Optimization of medium for carotenoids production by Arthrobacter sp. PAMC 25486 using response surface methodology
Other Titles
반응표면분석법을 이용한 Arthrobacter sp. PAMC 25486의 카로티노이드 생산배지 최적화
Authors
Kim, Hyun-do
Han, Se Jong
Choi, Jong-il
Keywords
Arthrobacter sp.; Carotenoid; Response surface methodology
Issue Date
2014
Citation
Kim, Hyun-do, Han, Se Jong, Choi, Jong-il. 2014. "Optimization of medium for carotenoids production by Arthrobacter sp. PAMC 25486 using response surface methodology". Korean Chemical Engineering Research(HWAHAK KONGHAK), 52(6): 834-839.
Abstract
This study was conducted to optimize the medium composition for carotenoid production in Arthrobacter sp. PAMC 25486 through response surface methodology (RSM). Using a Placket-Burman design, from which yeast extract, MgSO4 and dextrose were identified as the significant factors affecting carotenoids production. RSM studies for carotenoids production by Arthrobacter sp. PAMC 25486 have been carried out for three parameters of yeast extract, MgSO4 and dextrose concentrations. These significant factors were optimized by experiments and RSM, as 1 g/L yeast extract, 0.0879 g/L MgSO4 and 1 g/L dextrose. The experimentally obtained concentration of carotenoid was 288 mg/L, and it became 2-fold increase on concentration before optimization.
URI
http://repository.kopri.re.kr/handle/201206/7314
DOI
http://dx.doi.org/10.9713/kcer.2014.52.6.834
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