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바지락 MT 단백질의 Cd 노출에 대한 지표 활용성

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Title
바지락 MT 단백질의 Cd 노출에 대한 지표 활용성
Authors
Ahn, In-Young
Ji, Jungyoun
Choi, Heeseon J.
Keywords
Ruditapes philippinarum; biomarker; cadmium; metal-binding proteins; metallothioneins
Issue Date
2004
Citation
Ahn, In-Young, Ji, Jungyoun, Choi, Heeseon J.. 2004. 바지락 MT 단백질의 Cd 노출에 대한 지표 활용성. 한국과학재단(KOSEF) & 미국과학재단(NSF). 한국과학재단(KOSEF) & 미국과학재단(NSF). 2004.10.03~.
Abstract
A low-molecular weight (ca 12kD) MT-like protein (MTLP) was experimentally induced in the cytosol of R. philippinarum. Elution profiles of gel filtration chromatography showed that most of the Cd accumulated was bound to the MTLP. Immuno-histochemical analysis showed distinct antibody reactions in the epithelial cells of diverticula and of gill lamellae, which confirmed the presence of MT. The amount of Cd bound to MTLP was shown to increase with the increase of exposure time, indicating a potential utility of the MTLP as a biomarker to Cd exposure.
URI
http://repository.kopri.re.kr/handle/201206/7527
Conference Name
한국과학재단(KOSEF) & 미국과학재단(NSF)
Conference Place
한국과학재단(KOSEF) & 미국과학재단(NSF)
Conference Date
2004.10.03~
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