KOPRI Repository

The genome sequence of the Antarctic bullhead notothen reveals evolutionary adaptations to a cold environment

Cited 62 time in wos
Cited 62 time in scopus
Title
The genome sequence of the Antarctic bullhead notothen reveals evolutionary adaptations to a cold environment
Other Titles
남극대구 유전체 분석을 통한 저온적응기작 규명
Authors
Kim, Mi-Kyeong
Lee, Hyoungseok
Pyo, Chul Woo
Kim, Su Jin
Ahn, Do Hwan
Shin, Seung Chul
Park, Hyun
Lee, Jun Hyuck
Lee, Sung Gu
David Edwards
John H. Postlethwait
William Detrich
Lee, Jong Eun
Lee, Jong Eun
Keywords
Notothenia coriicepsevolutionheat shock responsewhole genome sequencing
Issue Date
2014
Citation
Kim, Mi-Kyeong, et al. 2014. "The genome sequence of the Antarctic bullhead notothen reveals evolutionary adaptations to a cold environment". GENOME BIOLOGY, 15(9): 468-468.
Abstract
Background Antarctic fish have adapted to the freezing waters of the Southern Ocean. Representative adaptations to this harsh environment include a constitutive heat shock response and the evolution of an antifreeze protein in the blood. Despite their adaptations to the cold, genome-wide studies have not yet been performed on these fish due to the lack of a sequenced genome. Notothenia coriiceps, the Antarctic bullhead notothen, is an endemic teleost fish with a circumpolar distribution and makes a good model to understand the genomic adaptations to constant sub-zero temperatures. Results We provide the draft genome sequence and annotation for N. coriiceps. Comparative genome-wide analysis with other fish genomes shows that mitochondrial proteins and hemoglobin evolved rapidly. Transcriptome analysis of thermal stress responses find alternative response mechanisms for evolution strategies in a cold environment. Loss of the phosphorylation-dependent sumoylation motif in heat shock factor 1 suggests that the heat shock response evolved into a simple and rapid phosphorylation-independent regulatory mechanism. Rapidly evolved hemoglobin and the induction of a heat shock response in the blood may support the efficient supply of oxygen to cold-adapted mitochondria. Conclusions Our data and analysis suggest that evolutionary strategies in efficient aerobic cellular respiration are controlled by hemoglobin and mitochondrial proteins, which may be important for the adaptation of Antarctic fish to their environment. The use of genome data from the Antarctic endemic fish provides an invaluable resource providing evidence of evolutionary adaptation and can be applied to other studies of Antarctic fish
URI
https://repository.kopri.re.kr/handle/201206/8552
DOI
http://dx.doi.org/10.1186/s13059-014-0468-1
Type
Article
Indexed
SCI
Appears in Collections  
2010-2012, Antarctic fish genome project (10-12) / Park, Hyun (PK10010, PE11150)
2014-2016, Antarctic Organisms: Cold-Adaptation Mechanism and Its Application (14-16) / Park; Hyun (PE14070; PE15070; PE16070)
Files in This Item

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse