Bioactive Terphenyls Isolated from the Antarctic Lichen Stereocaulon alpinum
DC Field | Value | Language |
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dc.contributor.author | Phi Kim Hoa | - |
dc.contributor.author | 신민지 | - |
dc.contributor.author | 이슬아 | - |
dc.contributor.author | So, Jae Eun | - |
dc.contributor.author | Kim, Ji Hee | - |
dc.contributor.author | 서승석 | - |
dc.contributor.author | Koo, Man Hyung | - |
dc.contributor.author | Shin, Seung Chul | - |
dc.contributor.author | Kim, Jin-Hyoung | - |
dc.contributor.author | Lee, Jun Hyuck | - |
dc.contributor.author | Youn, Ui Joung | - |
dc.date.accessioned | 2022-08-29T16:36:39Z | - |
dc.date.available | 2022-08-29T16:36:39Z | - |
dc.date.issued | 2022 | - |
dc.identifier.uri | https://repository.kopri.re.kr/handle/201206/13782 | - |
dc.description.abstract | Three p-terphenyls (2?4)―2-hydroxy-3,5-dimethoxy-p-terphenyl (2), 2-hydroxy-3,6-dimethoxy-p-terphenyl (3), and 2,3,5,6-tetramethoxy-p-terphenyl (4)―were iso-lated for the first time as natural products along with seven known compounds (1, 5?10) from the Antarctic lichen Stereocaulon alpinum. Structures of the new compounds were elucidated by com-prehensive analyses of 1D and 2D NMR and HREIMS experiments. Compound 3 exhibited cyto-toxicity against HCT116 cells with the IC50 value of 3.76 ± 0.03 μM and also inhibited NO production in LPS-induced RAW264.7 macrophages with the IC50 value of 22.82 ± 0.015 μM. | - |
dc.language | English | - |
dc.subject.classification | King Sejong Station | - |
dc.title | Bioactive Terphenyls Isolated from the Antarctic Lichen Stereocaulon alpinum | - |
dc.title.alternative | 남극 지의류인 Stereocaulon alpinum으로부터 분리된 생리활성을 가진 terphenyls | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | Phi Kim Hoa, et al. 2022. "Bioactive Terphenyls Isolated from the Antarctic Lichen Stereocaulon alpinum". <em>MOLECULES</em>, 27(7): 2363-2370. | - |
dc.citation.title | MOLECULES | - |
dc.citation.volume | 27 | - |
dc.citation.number | 7 | - |
dc.identifier.doi | 10.3390/molecules27072363 | - |
dc.citation.startPage | 2363 | - |
dc.citation.endPage | 2370 | - |
dc.description.articleClassification | SCIE | - |
dc.description.jcrRate | JCR 2020:35.393 | - |
dc.identifier.localId | 2022-0061 | - |
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