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Advantages of Single-Molecule Real-Time Sequencing in High-GC Content Genomes

Cited 47 time in wos
Cited 43 time in scopus
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dc.contributor.authorShin, Seung Chul-
dc.contributor.authorPark, Hyun-
dc.contributor.authorLee, Jong Eun-
dc.contributor.authorOh, Tae-Jin-
dc.contributor.authorLee, Hyoungseok-
dc.contributor.authorKim, Su Jin-
dc.contributor.authorAhn, Do Hwan-
dc.date.accessioned2018-03-20T13:56:02Z-
dc.date.available2018-03-20T13:56:02Z-
dc.date.issued2013-
dc.identifier.urihttps://repository.kopri.re.kr/handle/201206/6463-
dc.description.abstractNext-generation sequencing has become the most widely used sequencing technology in genomics research, but it has inherent drawbacks when dealing with high-GC content genomes. Recently, single-molecule real-time sequencing technology (SMRT) was introduced as a third-generation sequencing strategy to compensate for this drawback. Here, we report that the unbiased and longer read length of SMRT sequencing markedly improved genome assembly with high GC content via gap filling and repeat resolutionT) was introduced as a third-generation sequencing strategy to compensate for this drawback. Here, we report that the unbiased and longer read length of SMRT sequencing markedly improved genome assembly with high GC content via gap filling and repeat resolution-
dc.languageEnglish-
dc.publisherPublic-
dc.subjectScience & Technology - Other Topics-
dc.titleAdvantages of Single-Molecule Real-Time Sequencing in High-GC Content Genomes-
dc.title.alternativeSingle-Molecule Real-Time Sequencing 기법을 이용한 high-gc content 게몬분석-
dc.typeArticle-
dc.identifier.bibliographicCitationShin, Seung Chul, et al. 2013. "Advantages of Single-Molecule Real-Time Sequencing in High-GC Content Genomes". <em>PLOS ONE</em>, 8: e68824-e68824.-
dc.citation.titlePLOS ONE-
dc.citation.volume8-
dc.identifier.doi10.1371/journal.pone.0068824-
dc.citation.startPagee68824-
dc.citation.endPagee68824-
dc.description.articleClassificationSCIE-
dc.description.jcrRateJCR 2011:12.5-
dc.identifier.localId2013-0280-
dc.identifier.scopusid2-s2.0-84880715396-
dc.identifier.wosid000325211000041-
Appears in Collections  
2011-2013, Functional genomics on polar organisms (11-13) / Park, Hyun
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