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Antioxidant, antibacterial activity and brine shrimp toxicity test of some mountainous lichens from Nepal

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Cited 20 time in scopus
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dc.contributor.authorBabita Paudel-
dc.contributor.authorYim, Joung Han-
dc.contributor.authorKim, Il-Chan-
dc.contributor.authorHong, Soon Gyu-
dc.contributor.authorHur, Jae-Seoun-
dc.contributor.authorDurga Prasad Pandey-
dc.contributor.authorHari Datta Bhattarai-
dc.date.accessioned2018-03-20T13:59:22Z-
dc.date.available2018-03-20T13:59:22Z-
dc.date.issued2012-
dc.identifier.urihttps://repository.kopri.re.kr/handle/201206/6532-
dc.description.abstractA total of twenty four lichen species belonging to six families were collected from mountainous region of Nepal. The methanol extracts of each species were tested for antimicrobial and antioxidant activities in vitro. It was found that extracts of twenty one lichen species were active against B. subtilis and seven species were active against S. aureus. Similarly, in DPPH assay, three species Peltigera sp., Cladonia sp., and Canoparmelia sp. showed comparable activity with commercial standard, BHA. In ABTS+ assay, extracts of Parmoterma sp., Ramalina sp., Peltigera sp. and Cladonia sp. showed stronger activity than ascorbic acid. The observed data after comparison with previously published reports indicated that the high altitude lichens contain stronger antioxidant and antibacterial constituents. Similarly, the methanol extracts of Heterodermia sp. and Ramalina sp. showed comparable toxicity eff ect with commercial standard berberine chloride indicating a potent source of anticancer drugs.racts of twenty one lichen species were active against B. subtilis and seven species were active against S. aureus. Similarly, in DPPH assay, three species Peltigera sp., Cladonia sp., and Canoparmelia sp. showed comparable activity with commercial standard, BHA. In ABTS+ assay, extracts of Parmoterma sp., Ramalina sp., Peltigera sp. and Cladonia sp. showed stronger activity than ascorbic acid. The observed data after comparison with previously published reports indicated that the high altitude lichens contain stronger antioxidant and antibacterial constituents. Similarly, the methanol extracts of Heterodermia sp. and Ramalina sp. showed comparable toxicity eff ect with commercial standard berberine chloride indicating a potent source of anticancer drugs.-
dc.languageEnglish-
dc.publisherSciELO-
dc.subjectLife Sciences & Biomedicine - Other Topics-
dc.titleAntioxidant, antibacterial activity and brine shrimp toxicity test of some mountainous lichens from Nepal-
dc.title.alternative네팔 산악지역 지의류의 항산화, 항균 효과 분석-
dc.typeArticle-
dc.identifier.bibliographicCitationBabita Paudel, et al. 2012. "Antioxidant, antibacterial activity and brine shrimp toxicity test of some mountainous lichens from Nepal". <em>BIOLOGICAL RESEARCH</em>, 45(4): 387-391.-
dc.citation.titleBIOLOGICAL RESEARCH-
dc.citation.volume45-
dc.citation.number4-
dc.identifier.doi10.4067/S0716-97602012000400010-
dc.citation.startPage387-
dc.citation.endPage391-
dc.description.articleClassificationSCIE-
dc.description.jcrRateJCR 2010:77.90697674418605-
dc.subject.keywordAntibacterial-
dc.subject.keywordAntioxidant-
dc.subject.keywordFree radicals-
dc.subject.keywordNepal lichens-
dc.identifier.localId2013-0359-
dc.identifier.scopusid2-s2.0-84875339364-
dc.identifier.wosid000314144500010-
Appears in Collections  
2011-2013, Utilization of novel metabolites from polar organisms (11-13) / Yim, Joung Han
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