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Effects of Temperature and Solvents on the Stability of Algicidal Agent Prodigiosin

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dc.contributor.authorPark, Heeyong-
dc.contributor.authorYim, Joung Han-
dc.contributor.authorHan, Se Jong-
dc.contributor.authorKim, Tai Kyoung-
dc.contributor.authorLee, Sung Gu-
dc.description.abstractTo develop prodigiosin as biological control agent against Chattonella antiqua, a harmful alga that can cause red tides, selection of an organic solvent for prodigiosin extraction from culture broth and a test to determine the stability of prodigiosin were performed. Prodigiosin was extracted using nine solvents, and extracts were analyzed by LC-MS. Acetone was selected as the best organic solvent because of its high extraction efficiency and less process time. Stability tests for progidiosin were performed at various temperatures, and algicidal activity against C. antiqua was also tested. Ultimately, more than 98% stability was sustained after 30 days at 4℃, and less than 30% stability was maintained after 30 days at 37℃. More than 5~14% of the algicidal activity of prodigiosin extracted with acetone was sustained at each temperature, when compared with the prodigiosin extracted with ethanol. Although prodigiosin was kept for 30 days in an optimum organic solvent, the stability of prodigiosin was safely maintained and algicidal activity was sustained at low temperatures such as 4℃. Considering these results, we know that acetone was a very useful extraction agent for the extraction of prodigiosin as a biological control agent. [This work was supported by grants from the Korea Polar Research Institute (PE11060 and PN07020).]-
dc.titleEffects of Temperature and Solvents on the Stability of Algicidal Agent Prodigiosin-
dc.title.alternative살조물질 프로디지오신의 안정성에 대한 온도와 용매의 영향-
dc.identifier.bibliographicCitationPark, Heeyong, et al. 2012. Effects of Temperature and Solvents on the Stability of Algicidal Agent Prodigiosin. The Korean Society for Biotechnology and Bioengineering. The Korean Society for Biotechnology and Bioengineering. 2012.04.11~.-
dc.citation.conferenceNameThe Korean Society for Biotechnology and Bioengineering-
dc.citation.conferencePlaceThe Korean Society for Biotechnology and Bioengineering-
dc.subject.keywordAlgicidal activity-
dc.subject.keywordRed tide-
Appears in Collections  
2011-2013, Utilization of novel metabolites from polar organisms (11-13) / Yim, Joung Han
2005-2008, Development of algicidal agent using genomic informations of Hahella chejuensis (05-08) / Lee, Hong Kum; Yim, Joung Han
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