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A New Chlorinated Phenolic Compound From the Antarctic Lichen, Pertusaria dactylina

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Title
A New Chlorinated Phenolic Compound From the Antarctic Lichen, Pertusaria dactylina
Other Titles
남극 지의류, Pertusaria dactylina로부터 신규의 염소치환된 페놀성 화합물
Authors
Koo, Man Hyung
Kim, Min Ju
So, Jae Eun
Kim, Ji Hee
Han, Se Jong
Kim, Il-Chan
Lee, Jun Hyuck
Youn, Ui Joung
Subject
Pharmacology & Pharmacy; Food Science & Technology
Keywords
Pertusaria dactylina; Antarctic lichen; Pertusariaceae; antimicrobial activity; phenolic compound
Issue Date
2020-03
Citation
Koo, Man Hyung, et al. 2020. "A New Chlorinated Phenolic Compound From the Antarctic Lichen, Pertusaria dactylina". NATURAL PRODUCT COMMUNICATIONS, 15(3): 1-4.
Abstract
A new chlorinated phenolic compound, methyl-3-chloro-2-hydroxy-4-methoxy-6-pentylbenzoate (1) and four known compounds (2-5) were isolated from the Antarctic lichen, Pertusaria dactylina (Pertusariaceae). The structure of the new compound was determined by means of 1D and 2D NMR and HRFABMS experiments. The antimicrobial activities of compounds 15 against Staphylococcus aureus and Candida albicans were evaluated. The results showed that compound 1 exhibited a weak inhibitory effect against C. albicans with an IC50 value of 67 ± 7 μg/mL.
URI
https://repository.kopri.re.kr/handle/201206/12091
DOI
http://dx.doi.org/10.1177/1934578X20902886
Appears in Collections  
2019-2019, Development of potential candidates as antibiotics based on polar genetic resources (19-19) / Lee, Jun Hyuck (PE19210)
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