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Stereocalpin A, a bioactive cyclic depsipeptide from the Antarctic lichen Stereocaulon alpinum

Cited 37 time in wos
Cited 38 time in scopus
Title
Stereocalpin A, a bioactive cyclic depsipeptide from the Antarctic lichen Stereocaulon alpinum
Other Titles
남극 지의류 유래 bioactive cyclic depsipeptide인 Stereocalpin A
Authors
Lee, Hong Kum
Park, Seong Min
Oh, Hyuncheol
Yim, Joung Han
Seo, Changon
Sohn, Jae Hak
Subject
ImmunologyMarine & Freshwater BiologyVeterinary Sciences
Keywords
Cyclic depsipeptidStereocalpin AStereocaulon alpinumFisheries
Issue Date
2008
Citation
Lee, Hong Kum, et al. 2008. "Stereocalpin A, a bioactive cyclic depsipeptide from the Antarctic lichen Stereocaulon alpinum". TETRAHEDRON LETTERS, 18(0): 772-775.
Abstract
A new cyclic depsipeptide stereocalpin A (1) has been isolated from the MeOH extract of the Antarctic lichen Stereocaulon alpinum by various chromatographic methods. The structure of stereocalpin A (1) was mainly determined by analysis of the NMR spectroscopic data and by chemical methods. Stereocalpin A (1) is a unique cyclic peptide incorporating an unprecedented 5-hydroxy-2,4-dimethyl-3-oxo-octanoic acid in the structure. Stereocalpin A (1) shows moderate cytotoxicity against three human solid tumor cell lines. (C) 2007 Elsevier Ltd. All rights reserved.
URI
https://repository.kopri.re.kr/handle/201206/6317
DOI
http://dx.doi.org/10.1016/j.tetlet.2007.11.022
Type
Article
Indexed
SCI
Appears in Collections  
2006-2010, Procurement and utilization of polar genetic resources (06-10) / Lee, Hong Kum; Yim, Joung Han (PE06050, PE07050, PE08050, PE09050, PE10050)
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