Initial Degradative Pathways for Tetralin and Indene by Rhodococcus sp. strain DK17
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- Initial Degradative Pathways for Tetralin and Indene by Rhodococcus sp. strain DK17
- Other Titles
- Rhodococcus sp. strain DK17 의 tetralin과 indene 초기 분해경로 규명
- Kim, Dockyu
Jung Nam Choi
Ki Young Choi
Choong Hwan Lee
- Alkylbenzene dioxygenase; Indene; Rhodococcus; Tetralin
- Issue Date
- Kim, Dockyu, et al. 2008. Initial Degradative Pathways for Tetralin and Indene by Rhodococcus sp. strain DK17. 한국미생물학회. 한국미생물학회. 2008.05.15~.
- Rhodococcus sp. strain DK17, originally isolated for the ability to grow on o-xylene, was characterized to initiate the oxidative metabolism with alkylbenzene dioxygenase (AkbA1A2A3). Tetralin and indene are bicyclic compounds containing one aromatic ring plus one alicyclic ring, the structure of which is similar to that of o-xylene. DK17 was tested to characterize the metabolic pathway(s) of tetralin and indene. The initial metabolism of tetralin was shown to proceed via hydroxylation of the aromatic ring at positions C-1 and C-2, resulting in corresponding 5,6,7,8-tetrahydro-1,2-naphthalene diol. While the alicyclic ring of indene was dihydroxylated on an unsaturated double bond at C-1 and C-2 to indan-1,2-diol, which subsequently dehydrogenated to re-cyclized 1,2-indenediol.
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