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Genome-wide identification and structural analysis of heat shock protein gene families in the marine rotifer Brachionus spp.: Potential application in molecular ecotoxicology

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Title
Genome-wide identification and structural analysis of heat shock protein gene families in the marine rotifer Brachionus spp.: Potential application in molecular ecotoxicology
Other Titles
극지 요각류 Brachionus spp의 heat shock protein의 역활
Authors
Park, Jun Chul
Kim, Duck-Hyun
Lee, Yoseop
Lee, Min-Chul
Kim, Tai Kyoung
Yim, Joung Han
Lee, Jae-Seong
Subject
Biochemistry & Molecular Biology; Genetics & Heredity
Keywords
Stress proteins; Molecular chaperones; Invertebrates; Rotifer
Issue Date
2020-12
Citation
Park, Jun Chul, et al. 2020. "Genome-wide identification and structural analysis of heat shock protein gene families in the marine rotifer Brachionus spp.: Potential application in molecular ecotoxicology". COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS, 36(1): 100749-100749.
Abstract
Heat shock proteins (Hsp) are class of conserved and ubiquitous stress proteins present in all living organisms from primitive to higher level. Various studies have demonstrated multiple cellular functions of Hsp in living organisms as an important biomarker in response to abiotic and biotic stressors including temperature, salinity, pH, hypoxia, environmental pollutants, and pathogens. However, full understanding on the mechanism and pathway involved in the induction of Hsp still remains challenging, especially in aquatic invertebrates. In this study, the entire Hsp family and subfamily members in the marine rotifers Brachionus spp., one of the cosmopolitan ecotoxicological model organisms, have been genome-widely identified. In Brachionus spp. Hsp family was comprised of Hsp10, small hsp (sHsp), Hsp40, Hsp60, Hsp70/105, and Hsp90, with highest number of genes found within Hsp40 DnaJ homolog subfamily C members. Also, the differences in the orientation of the conserved motifs within Hsp family may have induced differences in transcriptional gene modulation in response to thermal stress in Brachionus koreanus. Overall, Hsp family-specific domains were highly conserved in all three Brachionus spp., relative to Homo sapiens and across other animal taxa and these findings will be helpful for future ecotoxicological studies focusing on Hsps.
URI
https://repository.kopri.re.kr/handle/201206/11796
DOI
http://dx.doi.org/10.1016/j.cbd.2020.100749
Appears in Collections  
2020-2020, Commercialization of new Biomaterials from polar organisms (20-20) / Yim, Joung Han (PE20010)
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