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2024-2024, 극지 지의류 유래 치매치료제 실용화 연구 (24-24) / 임정한

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Project Code: PM24010

Project Name (Other): Development of new Alzheimer's anti-dementia medicine using polar lichen-derived metabolites

Principal Investigator: 임정한

Proejct Period: 2024-2024

Collection's Items (Sorted by Year in Descending order): 1 to 8 of 8

1 Article Trends and Challenges in Plant Cryopreservation Research: A Meta-Analysis of Cryoprotective Agent Development and Research Focus
식물 냉동 보존 연구의 동향과 과제: 식물 냉동 보호제 개발과 연구 동향에 대한 메타 분석

2025-02
Kang, Pilsung; Kim, Sung Jin; Park, Ha Ju; Han, Se Jong; Kim, Il-Chan; Lee, Hyoungseok; Yim, Joung Han
2 Article Anti-Neuroinflammatory Effects of Prenylated Indole Alkaloids from the Antarctic Fungus Aspergillus sp. Strain SF-7367
Anti-Neuroinflammatory Effects of Prenylated Indole Alkaloids from the Antarctic Fungus Aspergillus sp. Strain SF-7367

2025-01
Liu Zhiming; Yoon Chi-Su; Cao Thao Quyen; Lee Hwan; Kim, Il-Chan; Yim, Joung Han; Sohn Jae Hak; Lee Dong-Sung; Oh Hyuncheol
3 Article N 5-((perfluorophenyl)amino)glutamine regulates BACE1, tau phosphorylation, synaptic function, and neuroinflammation in Alzheimer's disease models
알츠하이머병 모델에서 BACE1, 타우 인산화, 시냅스 기능 및 신경 염증을 조절하는 N5-((퍼플루오로페닐)아미노)글루타민의 역할

2025
Kim, Jun-Sik; Cho, Yongeun; Lee, Jeongmi; Cho, Heewon; Han, Sukmin; Lee, Yeongyeong; Jeon, Yeji; Kim, Tai Kyoung; Hong, Ju-Mi; Im, Jeonghyeong; Chae, Minshik; Lee, Yujeong; Kim, Hyunwook; Park, Sang Yoon; Kim, Sung Hyun; Yim, Joung Han; Jo, Dong-Gyu
4 Article Synthesis and Biological Evaluation of Novel Ramalin Derivatives as Multi-Target Agents for Alzheimer's Disease
알츠하이머병의 다중 표적 치료제로서 새로운 라말린 유도체의 합성, 생물학적 평가

2025
Kim, Tai Kyoung; Hong, Ju-Mi; Cho, Yongeun; Jeon, Yeji; Cho, Heewon; Lee, Jeongmi; Kim, Jaewon; Kim, Kyung Hee; Kim, Il-Chan; Han, Se Jong; Oh Hyuncheol; Jo Dong-Gyu; Yim, Joung Han
5 Article RA-PR058, a novel ramalin derivative, reduces BACE1 expression and phosphorylation of tau in Alzheimer's disease mouse models
RA-PR058, 새로운 라말린 유도체가 알츠하이머병 생쥐 모델에서 BACE1 발현 및 타우 인산화 저해

2025
Lee, Jeongmi; Cho, Yongeun; Kim, Jun-Sik; Jeon, Yeji; Han, Sukmin; Cho, Heewon; Lee, Yeongyeong; Kim, Tai Kyoung; Hong, Ju-Mi; Lee, Yujeong; Byun, Yujung; Chae, Minshik; Park, Sunyoung; Palomera, Leon F.; Park, Sang Yoon; Kim, Hyunwook; Kim, Soyeong; Kang, Seongeun; Jee, Jun-Goo; An, Hongchan; Yim, Joung Han; Kim, Sung Hyun; Jo, Dong-Gyu
6 Article The neuroprotective and anti-neuroinflammatory effects of ramalin synthetic derivatives in BV2 and HT22 cells
BV2 및 HT22 세포에서 라말린 합성 유도체의 신경 보호 및 항신경 염증 효과

2025
Zhiming Liu; Chi-Su Yoon; Hwan Lee; Eunae Kim; Yim, Joung Han; Tai Kyoung Kim; Hyuncheol Oh; Dong-Sung Lee
7 Article Therapeutic Potential of Ramalin Derivatives with Enhanced Stability in the Treatment of Alzheimer’s Disease
향상된 안정성을 가진 라말린 유도체의 알츠하이머병 치료 잠재력

2024-11
Kim, Tai Kyoung; Hong, Ju-Mi; Kim, Jaewon; Kim, Kyung Hee; Han, Se Jong; Kim, Il-Chan; Oh, Hyuncheol; Jo, Dong-Gyu; Yim, Joung Han
8 Article Synthesis and Evaluation of Chloride-Substituted Ramalin Derivatives for Alzheimer's Disease Treatment
알츠하이머병 치료를 위한 염화물 치환 라말린 유도체의 합성 및 평가

2024-08
Cho Yongeun; Kim, Tai Kyoung; Kim, Jaewon; Lee Jeongmi; Hong, Ju-Mi; Cho Heewon; Kim Jun-Sik; Lee Yeongyeong; Kim, Kyung Hee; Kim, Il-Chan; Han, Se Jong; Oh Hyuncheol; Jo Dong-Gyu; Yim, Joung Han

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